- Alcohol & Hydroxybenzene & Ether[1]
- Aldehyde & Ketone & Chinone[1]
- Organic Acid[4]
- Other Organic Chemical[1]
- Catalyst[1]
- Chemical Auxiliary Agent[10]
- Daily Chemicals[10]
- Feed Additives[3]
- Food Additives[7]
- Other Inorganic Salts[1]
- Sulphate[1]
- Other Inorganic Chemicals[3]
- Oxide[1]
- Organic Intermediate[1]
- Other Chemicals[2]
- Polymer[3]
- Pharmaceutical[10]
- Contact Person : Mr. Wang Mac
- Company Name : Hangzhou Trigger Chemical Co., Ltd.
- Tel : 86-571-88807861
- Fax : 86-571-88807903
- Address : Zhejiang,Hangzhou,804, 4288 Jiangnan Avenue, Hangzhou, China
- Country/Region : China
- Zip : 310053
10-Hydroxycamptothecin
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10-Hydroxycamptothecin, the derivative of camptothecin, is a minor alkaloid isolated from Camptotheca acuminata (a tree native to mainland China), At present, as an alkaloid anticancer, It is the only known natural DNA Topo isomerase inhibitors.
Formula: C20H16N2O5
Molecular weight: 364.34
Structure:
Melting Point: 268-270°C
Appearance: Yellow Crystal
Content of Active Ingredient: 99.0%min(HPLC method)
Solubility: Soluble in methanol, chloroform, acetonitrile; insoluble in water, Its sodium salt is soluble in water, its organic solution has blue fluorescence.
Pharmacological activity: Anti-cancer activity
Indication: Anti-cancer drug, suitable for treatment of breast and rectum cancers, liver cancer, stomach cancer, malignant melanoma, small-cell lung cancer and leukemia.
Side effects: The major side effects of hydroxycamptothecin are potentially severe diarrhea, nausea, lowered leukocyte (white blood cell) counts and also damage bone marrow, but much less than camptothecin.
Packing: 10g/Tin, 50g/Tin
Storage: Store in cool and dry place, keep tightly closed
Period of Validity: 3 Years
10-Hydroxycamptothecin